TY - JOUR
KW - Animals
KW - Cytokines
KW - Humans
KW - Immunity, Cellular
KW - Killer Cells, Natural
KW - leprosy
KW - Lymphocyte Activation
KW - Lymphokines
KW - Mice
KW - Phagocytes
KW - T-Lymphocytes
AU - Kaplan G
AU - Cohn Z A
AB - <p>The intradermal injection of the purified protein derivative of tuberculin into lepromatous leprosy patients leads to a local cell-mediated immune response and to the extensive destruction of Mycobacterium leprae. This local response also occurs after intradermal injection of recombinant human interleukin-2; when administered over an 8-day period interleukin-2 evokes a systemic cell-mediated immune response and a reduction in the bacillary burden.</p>
BT - Current opinion in immunology
C1 - http://www.ncbi.nlm.nih.gov/pubmed/2054116?dopt=Abstract
DA - 1991 Feb
DO - 10.1016/0952-7915(91)90083-d
IS - 1
J2 - Curr. Opin. Immunol.
LA - eng
N2 - <p>The intradermal injection of the purified protein derivative of tuberculin into lepromatous leprosy patients leads to a local cell-mediated immune response and to the extensive destruction of Mycobacterium leprae. This local response also occurs after intradermal injection of recombinant human interleukin-2; when administered over an 8-day period interleukin-2 evokes a systemic cell-mediated immune response and a reduction in the bacillary burden.</p>
PY - 1991
SP - 91
EP - 6
T2 - Current opinion in immunology
TI - Leprosy and cell-mediated immunity.
VL - 3
SN - 0952-7915
ER -