TY - JOUR KW - Acute disease KW - Aged KW - Arthritis KW - Clofazimine KW - Dapsone KW - Diagnosis, Differential KW - Drug Therapy, Combination KW - Exanthema KW - Glucocorticoids KW - Humans KW - Leprostatic Agents KW - leprosy KW - Male KW - Middle Aged KW - Mycobacterium leprae KW - Peripheral nerves KW - Peripheral Nervous System Diseases KW - Rifampin KW - Treatment Outcome AU - Sheetal S AU - Arvind C AB -
Several forms of arthritis and rheumatism can sometimes complicate leprosy. However, its presentation as an acute onset arthritis is unusual. We report two adult male naïve patients who presented to our rheumatology outpatient clinic with acute onset inflammatory polyarthritis, skin rash and mild sensory neurodeficit. Borderline lepromatous leprosy (in type I lepra reaction) was diagnosed. We also refer to 19 case records of Hansen arthritis in the clinic database (1998-2007) from approximately 35,000 patients and a community study to highlight the missed diagnosis of Hansen's disease and its unusual association with rheumatoid arthritis. In countries like India where leprosy is endemic, this disease also merits attention in rheumatology clinics.
BT - International journal of rheumatic diseases C1 - http://www.ncbi.nlm.nih.gov/pubmed/20374320?dopt=Abstract DA - 2009 Apr DO - 10.1111/j.1756-185X.2009.01382.x IS - 1 J2 - Int J Rheum Dis LA - eng N2 -Several forms of arthritis and rheumatism can sometimes complicate leprosy. However, its presentation as an acute onset arthritis is unusual. We report two adult male naïve patients who presented to our rheumatology outpatient clinic with acute onset inflammatory polyarthritis, skin rash and mild sensory neurodeficit. Borderline lepromatous leprosy (in type I lepra reaction) was diagnosed. We also refer to 19 case records of Hansen arthritis in the clinic database (1998-2007) from approximately 35,000 patients and a community study to highlight the missed diagnosis of Hansen's disease and its unusual association with rheumatoid arthritis. In countries like India where leprosy is endemic, this disease also merits attention in rheumatology clinics.
PY - 2009 SP - 64 EP - 9 T2 - International journal of rheumatic diseases TI - Lest we forget Hansen's disease (leprosy): an unusual presentation with an acute onset of inflammatory polyarthritis and the rheumatology experience. VL - 12 SN - 1756-185X ER -