TY - JOUR KW - Adolescent KW - Adult KW - Aged KW - Dermatitis Herpetiformis KW - Eye diseases KW - Humans KW - leprosy KW - Leprosy, Borderline KW - Middle Aged KW - Pupil KW - Time Factors KW - Tuberculosis, Pulmonary AU - Karaçorlu M A AU - Sürel Z AU - Cakiner T AU - Hanyaloğlu E AU - Saylan T AU - Mat C AB -

Ocular complications of leprosy patients often develop insidiously and with few if any symptoms. This study involves measurement of the pupil cycle time (PCT) to evaluate the autonomic nerve system of the iris to determine the presence of subclinical intraocular involvement. The study included 19 lepromatous (LL), 19 borderline lepromatous (BL), and five borderline tuberculoid (BT) leprosy patients and involved 25 healthy volunteers, 10 patients with pulmonary tuberculosis and eight with Duhring disease. The PCT was measured in these groups. In all leprosy groups included in the study the PCT was higher than in the control groups. Moreover, the PCT of the leprosy patients without any intraocular involvement was higher than in the controls. These results show that in the ophthalmic examination of leprosy patients without any symptoms the fact that autonomic nerve system of the eye is affected by the leprosy can often be determined by measuring the PCT.

BT - The British journal of ophthalmology C1 - http://www.ncbi.nlm.nih.gov/pubmed/1991087?dopt=Abstract DA - 1991 Jan DO - 10.1136/bjo.75.1.45 IS - 1 J2 - Br J Ophthalmol LA - eng N2 -

Ocular complications of leprosy patients often develop insidiously and with few if any symptoms. This study involves measurement of the pupil cycle time (PCT) to evaluate the autonomic nerve system of the iris to determine the presence of subclinical intraocular involvement. The study included 19 lepromatous (LL), 19 borderline lepromatous (BL), and five borderline tuberculoid (BT) leprosy patients and involved 25 healthy volunteers, 10 patients with pulmonary tuberculosis and eight with Duhring disease. The PCT was measured in these groups. In all leprosy groups included in the study the PCT was higher than in the control groups. Moreover, the PCT of the leprosy patients without any intraocular involvement was higher than in the controls. These results show that in the ophthalmic examination of leprosy patients without any symptoms the fact that autonomic nerve system of the eye is affected by the leprosy can often be determined by measuring the PCT.

PY - 1991 SP - 45 EP - 8 T2 - The British journal of ophthalmology TI - Pupil cycle time and early autonomic involvement in ocular leprosy. UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC504106/pdf/brjopthal00061-0052.pdf VL - 75 SN - 0007-1161 ER -