Both wound healing and lymphedema have fibrosis of the skin in common. They also share destruction of elastin by elastases from neutrophils as a significant feature. These are not new observations, and the writings of Unna and Kaposi are recalled. The contemporary observations on elastin by Gerli and his team are discussed in the light of these much earlier opinions.
BT - Lymphology C1 - http://www.ncbi.nlm.nih.gov/pubmed/19499764?dopt=Abstract DA - 2009 Mar IS - 1 J2 - Lymphology LA - eng N2 -Both wound healing and lymphedema have fibrosis of the skin in common. They also share destruction of elastin by elastases from neutrophils as a significant feature. These are not new observations, and the writings of Unna and Kaposi are recalled. The contemporary observations on elastin by Gerli and his team are discussed in the light of these much earlier opinions.
PY - 2009 SP - 19 EP - 25 T2 - Lymphology TI - Elephantiasis, elastin, and chronic wound healing: 19th century and contemporary viewpoints relevant to hypotheses concerning lymphedema, leprosy, erysipelas, and psoriasis--review and reflections. VL - 42 SN - 0024-7766 ER -