These immunopathogenesis studies of leprosy have provided new insight into the immune response to M leprae at the site of disease activity, the skin lesions. The study of leprosy provides a model for studying the immune response to foreign pathogens as well as the immunopathologic study of skin lesions. Further developments in immunology and molecular biology will increase our ability to dissect such immune mechanisms. For example, the advent of the polymerase chain reaction will allow for a more complete elucidation of the cytokines in inflammatory skin lesions.
BT - Seminars in dermatology C1 - http://www.ncbi.nlm.nih.gov/pubmed/1931567?dopt=Abstract CN - REA1991 DA - 1991 Sep IS - 3 J2 - Semin Dermatol LA - eng N2 -These immunopathogenesis studies of leprosy have provided new insight into the immune response to M leprae at the site of disease activity, the skin lesions. The study of leprosy provides a model for studying the immune response to foreign pathogens as well as the immunopathologic study of skin lesions. Further developments in immunology and molecular biology will increase our ability to dissect such immune mechanisms. For example, the advent of the polymerase chain reaction will allow for a more complete elucidation of the cytokines in inflammatory skin lesions.
PY - 1991 SP - 188 EP - 93 T2 - Seminars in dermatology TI - Immunopathology of leprosy skin lesions. VL - 10 SN - 0278-145X ER -