Animal models for testing different vaccine candidates have been developed since a long time for studying tuberculosis. Mice, guinea pigs and rabbits are animals most frequently used. Each model has its own merits for studying human tuberculosis, and none completely mimics the human disease. Different animal models are being used depending upon the availability of the space, trained manpower as well as other resources. Efforts should continue to develop a vaccine which can replace/outperform the presently available vaccine BCG.
BT - The Indian journal of medical research C1 - http://www.ncbi.nlm.nih.gov/pubmed/19287053?dopt=Abstract DA - 2009 Jan IS - 1 J2 - Indian J. Med. Res. LA - eng N2 -Animal models for testing different vaccine candidates have been developed since a long time for studying tuberculosis. Mice, guinea pigs and rabbits are animals most frequently used. Each model has its own merits for studying human tuberculosis, and none completely mimics the human disease. Different animal models are being used depending upon the availability of the space, trained manpower as well as other resources. Efforts should continue to develop a vaccine which can replace/outperform the presently available vaccine BCG.
PY - 2009 SP - 11 EP - 8 T2 - The Indian journal of medical research TI - Animal models of tuberculosis for vaccine development. VL - 129 SN - 0971-5916 ER -