TY - JOUR KW - Adrenal Cortex Hormones KW - Aged KW - Aspirin KW - Clofazimine KW - Dapsone KW - Diagnosis, Differential KW - Female KW - Humans KW - Leprostatic Agents KW - leprosy KW - Macrophages, Peritoneal KW - Mycobacterium lepraemurium KW - Rifampin AU - Gabelle A AU - Vallat J M AU - Flageul B AU - Andre P AU - Camu W AB -
The diagnostic process of sensory-motor neuropathies is difficult. Atypical variants and rare etiologies also contribute to delay the diagnosis. We report the case of a 70-year-old woman with slowly progressive asymmetric axonal sensory-motor neuropathy. Leprosy was identified after an eight-year delay. Nerve biopsy was required to establish the diagnosis: electron microscopy revealed debris of Hansen's bacillus in the nerve. Treatment was fully curative after several months. Leprosy is a rare cause of neuropathy in Europeans. Systematic inquiry about travel to endemic areas would be helpful in establishing the diagnosis. In such cases, nerve biopsy is crucial.
BT - Revue neurologique C1 - http://www.ncbi.nlm.nih.gov/pubmed/18808760?dopt=Abstract DA - 2008 Nov DO - 10.1016/j.neurol.2007.11.004 IS - 11 J2 - Rev. Neurol. (Paris) LA - fre N2 -The diagnostic process of sensory-motor neuropathies is difficult. Atypical variants and rare etiologies also contribute to delay the diagnosis. We report the case of a 70-year-old woman with slowly progressive asymmetric axonal sensory-motor neuropathy. Leprosy was identified after an eight-year delay. Nerve biopsy was required to establish the diagnosis: electron microscopy revealed debris of Hansen's bacillus in the nerve. Treatment was fully curative after several months. Leprosy is a rare cause of neuropathy in Europeans. Systematic inquiry about travel to endemic areas would be helpful in establishing the diagnosis. In such cases, nerve biopsy is crucial.
PY - 2008 SP - 964 EP - 8 T2 - Revue neurologique TI - [Sensory-motor neuropathy: a slow and misleading case of leprosy]. VL - 164 SN - 0035-3787 ER -