TY - JOUR KW - Adolescent KW - Adult KW - Female KW - Humans KW - Leprostatic Agents KW - Leprosy, Borderline KW - Leprosy, lepromatous KW - Male KW - Median Nerve KW - Mycobacterium leprae KW - Peripheral nerves KW - Tibial Nerve KW - Time Factors AU - Pereira J H AU - Palande D D AU - Gschmeissner S E AB -

Mycobacteria were present in 4 out of 8 mixed peripheral nerve trunks from patients (3 BT and 1 BL) treated with DDS and/or MDT for periods ranging from 21 months to 8 years. Most of the bacilli appeared to be 'whole'. Nerve destruction with areas of granulomatous infiltration appeared more active than expected. Possible reasons for a continued presence of bacilli in treated nerves and its implications in 'relapse' are discussed.

BT - Leprosy review C1 - http://www.ncbi.nlm.nih.gov/pubmed/1870375?dopt=Abstract CN - Infolep Library - available DA - 1991 Jun DO - 10.5935/0305-7518.19910015 IS - 2 J2 - Lepr Rev LA - eng N2 -

Mycobacteria were present in 4 out of 8 mixed peripheral nerve trunks from patients (3 BT and 1 BL) treated with DDS and/or MDT for periods ranging from 21 months to 8 years. Most of the bacilli appeared to be 'whole'. Nerve destruction with areas of granulomatous infiltration appeared more active than expected. Possible reasons for a continued presence of bacilli in treated nerves and its implications in 'relapse' are discussed.

PY - 1991 SP - 134 EP - 42 T2 - Leprosy review TI - Mycobacteria in nerve trunks of long-term treated leprosy patients. UR - http://leprev.ilsl.br/pdfs/1991/v62n2/pdf/v62n2a03.pdf VL - 62 SN - 0305-7518 ER -