In lepromatous leprosy, blood vessels revealed the luminal protrusions of endothelial cells containing M. leprae and thickening of the basement membrane of endothelial and smooth cells. Endothelial projections with increased pinocytotic vesicles were more often encountered in lepromatous leprosy than in the other types of leprosy. On the other hand, in tuberculoid leprosy, the extensive rough endoplasmic reticulum suggesting protein synthesis was observed in the endothelial cells compared with the other types of leprosy and non-specific lesions. It seems that the blood vessels associated with hyperfunction and proliferation in the endothelium could aggravate the degenerative changes in peripheral nerve fibers including the Schwann cells.
BT - Nihon Rai Gakkai zasshi C1 - http://www.ncbi.nlm.nih.gov/pubmed/1843224?dopt=Abstract DA - 1991 Jul-Dec DO - 10.5025/hansen1977.60.121 IS - 3-4 J2 - Nihon Rai Gakkai Zasshi LA - eng N2 -In lepromatous leprosy, blood vessels revealed the luminal protrusions of endothelial cells containing M. leprae and thickening of the basement membrane of endothelial and smooth cells. Endothelial projections with increased pinocytotic vesicles were more often encountered in lepromatous leprosy than in the other types of leprosy. On the other hand, in tuberculoid leprosy, the extensive rough endoplasmic reticulum suggesting protein synthesis was observed in the endothelial cells compared with the other types of leprosy and non-specific lesions. It seems that the blood vessels associated with hyperfunction and proliferation in the endothelium could aggravate the degenerative changes in peripheral nerve fibers including the Schwann cells.
PY - 1991 SP - 121 EP - 7 T2 - Nihon Rai Gakkai zasshi TI - Ultrastructural observations of small blood vessels in leprosy patients. VL - 60 SN - 0386-3980 ER -