A comparative study of lymphocyte subpopulations from leprosy patients were carried out using nonspecific esterase (ANAE) staining and monoclonal antibodies. Regardless of the methodology used, an intense reduction in the total number of the T helper/inducer subset and an inversion of the helper/suppressor ration could be observed. These alterations were more evident with the progress of the disease from the tuberculoid (TL) to the lepromatous (LL) pole. Thus ANAE may be considered an economical and reliable method to be used in the study of the immune status of leprosy patients.
BT - Experimental pathology C1 - http://www.ncbi.nlm.nih.gov/pubmed/1827072?dopt=Abstract DA - 1991 DO - 10.1016/s0232-1513(11)80046-0 IS - 1 J2 - Exp Pathol LA - eng N2 -A comparative study of lymphocyte subpopulations from leprosy patients were carried out using nonspecific esterase (ANAE) staining and monoclonal antibodies. Regardless of the methodology used, an intense reduction in the total number of the T helper/inducer subset and an inversion of the helper/suppressor ration could be observed. These alterations were more evident with the progress of the disease from the tuberculoid (TL) to the lepromatous (LL) pole. Thus ANAE may be considered an economical and reliable method to be used in the study of the immune status of leprosy patients.
PY - 1991 SP - 50 EP - 2 T2 - Experimental pathology TI - Nonspecific esterase staining of lymphocyte subsets in leprosy. VL - 41 SN - 0232-1513 ER -