TY - JOUR KW - Animals KW - Colony Count, Microbial KW - Dapsone KW - Drug Evaluation, Preclinical KW - Leprostatic Agents KW - leprosy KW - Mice KW - Mice, Inbred CBA KW - Mycobacterium leprae KW - Thiocarbamates AU - Urlyapova N G AU - Yushchenko A A AU - Daudova A D AU - Makarov V A AB -

Effects of some dialkyldithiocarbamate derivatives on multiplication of M. leprae were studied in infected mice. Compounds significantly suppressing M. leprae proliferation were selected. By antibacterial activity one of these compounds was superior to dapsone, the main antileprosy drug.

BT - Bulletin of experimental biology and medicine C1 - http://www.ncbi.nlm.nih.gov/pubmed/18225763?dopt=Abstract DA - 2007 Mar DO - 10.1007/s10517-007-0111-1 IS - 3 J2 - Bull. Exp. Biol. Med. LA - eng N2 -

Effects of some dialkyldithiocarbamate derivatives on multiplication of M. leprae were studied in infected mice. Compounds significantly suppressing M. leprae proliferation were selected. By antibacterial activity one of these compounds was superior to dapsone, the main antileprosy drug.

PY - 2007 SP - 356 EP - 8 T2 - Bulletin of experimental biology and medicine TI - Study of antileprosy activities of some dialkyldithiocarbamate derivatives. VL - 143 SN - 0007-4888 ER -