TY - JOUR KW - Animals KW - Cell Line KW - Dapsone KW - leprosy KW - Mice KW - Mice, Inbred CBA KW - Mycobacterium leprae KW - Rifampin KW - Tuftsin AU - Vishnevetskiĭ F E AU - Freĭdlin I S AU - Iushchenko A A AU - Vishnevetskiĭ R F AU - Anokhina V V AU - Urliapova N G AU - Iushin IM AU - Eskina I M AB -
The effect of tuftsin was studied in vivo using CBA mice infected with M. leprae by Shepard's technique and in vitro using macrophage-like cell line P. 388 (Co-cultivated with M. leprae) and the cultivated leproma tissue. It was found out that tuftsin acted as a stimulator of M. leprae multiplication in foot-pads of mice and as a prolongator of M. leprae survival in the cells of macrophage-like cell line P .388. It is concluded that using tuftsin might be useful in view of studying different aspects of experimental leprosy.
BT - Biulleten' eksperimental'noi biologii i meditsiny C1 - http://www.ncbi.nlm.nih.gov/pubmed/1786385?dopt=Abstract DA - 1991 Aug IS - 8 J2 - Biull Eksp Biol Med LA - rus N2 -The effect of tuftsin was studied in vivo using CBA mice infected with M. leprae by Shepard's technique and in vitro using macrophage-like cell line P. 388 (Co-cultivated with M. leprae) and the cultivated leproma tissue. It was found out that tuftsin acted as a stimulator of M. leprae multiplication in foot-pads of mice and as a prolongator of M. leprae survival in the cells of macrophage-like cell line P .388. It is concluded that using tuftsin might be useful in view of studying different aspects of experimental leprosy.
PY - 1991 SP - 181 EP - 3 T2 - Biulleten' eksperimental'noi biologii i meditsiny TI - [Use of tuftsin in experimental leprosy]. VL - 112 SN - 0365-9615 ER -