TY - JOUR
KW - Animals
KW - Armoracia
KW - Disease Models, Animal
KW - Drug Therapy, Combination
KW - Horseradish Peroxidase
KW - leprosy
KW - Mice
KW - Mice, Inbred CBA
KW - Neutrophils
KW - Peroxidase
KW - Plant Roots
KW - Potassium Iodide
KW - Rifampin
KW - Treatment Outcome
AU - Maslov A K
AU - Khivrina S A
AB - <p>A model of leprosy was used to study the therapeutic effect of horse-radish root (HRR) containing peroxidase in combination with rifampicin (RFP) and potassium iodide (PI) as compared to routine combined therapy with RFP and diaminodiphenylsulfonum. Therapy with HRR and iodide showed the best antimicrobial effect than the routine combined therapy. A combination of RFP, HRR, and PI increased the activity of neutrophilic myeliperoxidase produced an anti-inflammatory activity and caused no persistent anemia or toxic effect on the murine liver.</p>
BT - Problemy tuberkuleza i boleznei legkikh
C1 - http://www.ncbi.nlm.nih.gov/pubmed/17657964?dopt=Abstract
DA - 2007
IS - 4
J2 - Probl Tuberk Bolezn Legk
LA - rus
N2 - <p>A model of leprosy was used to study the therapeutic effect of horse-radish root (HRR) containing peroxidase in combination with rifampicin (RFP) and potassium iodide (PI) as compared to routine combined therapy with RFP and diaminodiphenylsulfonum. Therapy with HRR and iodide showed the best antimicrobial effect than the routine combined therapy. A combination of RFP, HRR, and PI increased the activity of neutrophilic myeliperoxidase produced an anti-inflammatory activity and caused no persistent anemia or toxic effect on the murine liver.</p>
PY - 2007
SP - 25
EP - 7
T2 - Problemy tuberkuleza i boleznei legkikh
TI - [Prospects for leprosy treatment via complexation of rifampicin witH iodide and horse-radish root].
SN - 1728-2993
ER -