TY - JOUR
KW - Adult
KW - Bone and Bones
KW - Female
KW - Gallium Radioisotopes
KW - Humans
KW - leprosy
KW - Liver
KW - Lung
KW - Male
KW - Radionuclide Imaging
KW - Skin
KW - Spleen
KW - Technetium Tc 99m Medronate
KW - Technetium Tc 99m Sulfur Colloid
AU - Braga F J
AU - Araújo E B
AU - Camargo E E
AU - Tedesco-Marchesi L C
AU - Rivitti M C
AU - Bouladour H
AU - Galle P
AB - <p>Gallium 67 imaging was used in 12 patients with documented Hansen's disease undergoing treatment or not, in an attempt to determine the pattern of the disease. Diagnosis was confirmed by histopathology in all patients. The Mitsuda reaction was seen in all patients. Specific nuclear studies were performed when needed to evaluate particular organs better. Gallium 67 images show homogeneous, diffuse and moderate accumulation over the entire skin surface (except for the face) of untreated patients with multibacillary disease. The facial skin in these cases presented homogeneous, diffuse but very marked uptake of gallium. Internal organ involvement was variable. There was a very good correlation among clinical, scintigraphic, immunological and histopathological data. The pattern of the body skin ("skin outlining") and facial skin ("beard distribution") may be distinct for untreated patients with multibacillary leprosy.</p>
BT - European journal of nuclear medicine
C1 - http://www.ncbi.nlm.nih.gov/pubmed/1752258?dopt=Abstract
DA - 1991
DO - 10.1007/bf02258451
IS - 11
J2 - Eur J Nucl Med
LA - eng
N2 - <p>Gallium 67 imaging was used in 12 patients with documented Hansen's disease undergoing treatment or not, in an attempt to determine the pattern of the disease. Diagnosis was confirmed by histopathology in all patients. The Mitsuda reaction was seen in all patients. Specific nuclear studies were performed when needed to evaluate particular organs better. Gallium 67 images show homogeneous, diffuse and moderate accumulation over the entire skin surface (except for the face) of untreated patients with multibacillary disease. The facial skin in these cases presented homogeneous, diffuse but very marked uptake of gallium. Internal organ involvement was variable. There was a very good correlation among clinical, scintigraphic, immunological and histopathological data. The pattern of the body skin ("skin outlining") and facial skin ("beard distribution") may be distinct for untreated patients with multibacillary leprosy.</p>
PY - 1991
SP - 866
EP - 9
T2 - European journal of nuclear medicine
TI - Gallium scintigraphy in Hansen's disease.
VL - 18
SN - 0340-6997
ER -