TY - JOUR
KW - Adolescent
KW - Child
KW - Combined Modality Therapy
KW - Drug Therapy, Combination
KW - Female
KW - Follow-Up Studies
KW - Humans
KW - Leprostatic Agents
KW - leprosy
KW - Male
KW - Neurologic Examination
KW - Peripheral nerves
KW - Retrospective Studies
KW - Treatment Outcome
AU - Ramarorazana S
AU - Rene J P
AU - Schwartzl E
AU - Randrianomenjanahary J
AU - Razafindramboa H
AU - Di Schino M
AB - <p>Surgical decompression of nerves in patients with leprosy is a simple procedure that can be used in developing countries. At the leprosy center of Ambatoabo on the east coast of Madagascar, 466 nerve decompressions were performed on 123 subjects and results were evaluated by the same examiner 15 months later. All subjects were undergoing multidrug therapy at the time of the procedure. The decision to perform surgery was based on recent onset of sensory and motor neurologic signs and on progression or persistence of symptoms despite administration of prednisolone. Decompression led to pain relief in 100% of cases and regression of sensory disturbances in 97%. Sensory recovery in the plantar ulcers of the foot was obtained in 80% of cases and motor performance improved in 61%. These favorable results confirm the value of surgical decompression to prevent sequels of leprosy and the feasibility of this procedure in remote areas.</p>
BT - Medecine tropicale : revue du Corps de sante colonial
C1 - http://www.ncbi.nlm.nih.gov/pubmed/7564996?dopt=Abstract
DA - 1995
IS - 2
J2 - Med Trop (Mars)
LA - fre
N2 - <p>Surgical decompression of nerves in patients with leprosy is a simple procedure that can be used in developing countries. At the leprosy center of Ambatoabo on the east coast of Madagascar, 466 nerve decompressions were performed on 123 subjects and results were evaluated by the same examiner 15 months later. All subjects were undergoing multidrug therapy at the time of the procedure. The decision to perform surgery was based on recent onset of sensory and motor neurologic signs and on progression or persistence of symptoms despite administration of prednisolone. Decompression led to pain relief in 100% of cases and regression of sensory disturbances in 97%. Sensory recovery in the plantar ulcers of the foot was obtained in 80% of cases and motor performance improved in 61%. These favorable results confirm the value of surgical decompression to prevent sequels of leprosy and the feasibility of this procedure in remote areas.</p>
PY - 1995
SP - 146
EP - 50
T2 - Medecine tropicale : revue du Corps de sante colonial
TI - [One-year follow-up of 466 nerve decompressions in 123 lepers during multidrug therapy in Madagascar].
VL - 55
SN - 0025-682X
ER -