TY - JOUR
KW - Adolescent
KW - Adult
KW - Antibodies, Bacterial
KW - Child
KW - Child, Preschool
KW - Female
KW - Humans
KW - Immunoglobulin M
KW - Indonesia
KW - Infant
KW - Latex Fixation Tests
KW - leprosy
KW - Male
KW - Mass Screening
KW - Middle Aged
KW - Mycobacterium leprae
KW - Prevalence
KW - Prospective Studies
KW - Seroepidemiologic Studies
KW - Suburban Health
AU - Hatta M
AU - Izumi S
AU - Klatser P R
AB - <p>This study reports on the usefulness of an IgM phenolic glycolipid-1 (PGL-1) Mycobacterium leprae particle agglutination (MLPA) test for serodiagnosis of leprosy in a prospective longitudinal community survey in a high prevalence village in South Sulawesi, Indonesia, IgM PGL-1 MLPA has simple and limited value as a screening method for detection of transmission of leprosy in the community. Many normal persons in the community in a high prevalence area had increased IgM anti PGL-1 antibodies, presumably as a consequence of early subclinical infection. In conclusion, this study demonstrated that the MLPA test can only reliably detect anti-PGL-1 antibodies in the community and may be useful for follow-up study of subclinical infection of leprosy among individuals living the an endemic area.</p>
BT - The Southeast Asian journal of tropical medicine and public health
C1 - http://www.ncbi.nlm.nih.gov/pubmed/9139365?dopt=Abstract
DA - 1995 Dec
IS - 4
J2 - Southeast Asian J. Trop. Med. Public Health
LA - eng
N2 - <p>This study reports on the usefulness of an IgM phenolic glycolipid-1 (PGL-1) Mycobacterium leprae particle agglutination (MLPA) test for serodiagnosis of leprosy in a prospective longitudinal community survey in a high prevalence village in South Sulawesi, Indonesia, IgM PGL-1 MLPA has simple and limited value as a screening method for detection of transmission of leprosy in the community. Many normal persons in the community in a high prevalence area had increased IgM anti PGL-1 antibodies, presumably as a consequence of early subclinical infection. In conclusion, this study demonstrated that the MLPA test can only reliably detect anti-PGL-1 antibodies in the community and may be useful for follow-up study of subclinical infection of leprosy among individuals living the an endemic area.</p>
PY - 1995
SP - 631
EP - 5
T2 - The Southeast Asian journal of tropical medicine and public health
TI - Evaluation of the Mycobacterium leprae particle agglutination (MLPA) test as a tool in the epidemiology of leprosy in high prevalence village in South Sulawesi, Indonesia.
VL - 26
SN - 0125-1562
ER -