TY - JOUR KW - Autoantibodies KW - Autoimmune Diseases KW - Autoimmunity KW - Cytokines KW - Humans KW - Immunity, Cellular KW - Immunoglobulin G KW - leprosy KW - Models, Biological KW - Mycobacterium KW - Mycobacterium Infections KW - Time Factors KW - Tuberculosis AU - Rook G A AU - Stanford J L AB -
In this article, Graham Rook and John Stanford propose that a group of idiopathic diseases that are often associated with a degree of autoimmunity and arthritis, including rheumatoid arthritis, inflammatory bowel disease, sarcoidosis and psoriasis, are caused by extremely slow-growing bacteria. They suggest that these diseases are one end of a continuous spectrum caused by related slow-growing genera, which ranges from rheumatoid arthritis, through Takayasu's arteritis and Whipple's disease, to reach the conventional mycobacterioses such as tuberculosis and leprosy.
BT - Immunology today C1 - http://www.ncbi.nlm.nih.gov/pubmed/1642753?dopt=Abstract DA - 1992 May DO - 10.1016/0167-5699(92)90119-R IS - 5 J2 - Immunol. Today LA - eng N2 -In this article, Graham Rook and John Stanford propose that a group of idiopathic diseases that are often associated with a degree of autoimmunity and arthritis, including rheumatoid arthritis, inflammatory bowel disease, sarcoidosis and psoriasis, are caused by extremely slow-growing bacteria. They suggest that these diseases are one end of a continuous spectrum caused by related slow-growing genera, which ranges from rheumatoid arthritis, through Takayasu's arteritis and Whipple's disease, to reach the conventional mycobacterioses such as tuberculosis and leprosy.
PY - 1992 SP - 160 EP - 4 T2 - Immunology today TI - Slow bacterial infections or autoimmunity? VL - 13 SN - 0167-5699 ER -