TY - JOUR
KW - Acetamides
KW - Animals
KW - Anti-Infective Agents
KW - Aza Compounds
KW - Diarylquinolines
KW - Female
KW - Fluoroquinolones
KW - leprosy
KW - Linezolid
KW - Mice
KW - Moxifloxacin
KW - Mycobacterium leprae
KW - Nitroimidazoles
KW - Oxazolidinones
KW - Quinolines
AU - Ji B
AU - Chauffour A
AU - Andries K
AU - Jarlier V
AB - <p>As measured by a proportional bactericidal technique in the mouse footpad system, the bactericidal activity against Mycobacterium leprae of R207910 was equal to that of rifapentine, rifampin, or moxifloxacin and significantly greater than those of minocycline, PA-824, and linezolid. These data suggest that R207910 may play an important role in treatment of leprosy.</p>
BT - Antimicrobial agents and chemotherapy
C1 - http://www.ncbi.nlm.nih.gov/pubmed/16569884?dopt=Abstract
DA - 2006 Apr
DO - 10.1128/AAC.50.4.1558-1560.2006
IS - 4
J2 - Antimicrob. Agents Chemother.
LA - eng
N2 - <p>As measured by a proportional bactericidal technique in the mouse footpad system, the bactericidal activity against Mycobacterium leprae of R207910 was equal to that of rifapentine, rifampin, or moxifloxacin and significantly greater than those of minocycline, PA-824, and linezolid. These data suggest that R207910 may play an important role in treatment of leprosy.</p>
PY - 2006
SP - 1558
EP - 60
T2 - Antimicrobial agents and chemotherapy
TI - Bactericidal activities of R207910 and other newer antimicrobial agents against Mycobacterium leprae in mice.
VL - 50
SN - 0066-4804
ER -