TY - JOUR KW - Adolescent KW - Adult KW - Age Factors KW - Child KW - Child, Preschool KW - Female KW - Humans KW - India KW - Infant KW - leprosy KW - Male KW - Pregnancy KW - Recurrence KW - Retrospective Studies KW - Sex Factors KW - Urban Health AU - Saha S P AU - Das K K AB -

In this retrospective study of the 3737 cases of leprosy released from treatment and followed-up during 1975 to 1990, 63 had relapsed giving an overall relapse rate of 1.69%. The relapse rate was significantly higher in the immunologically unstable N?L (Borderline) cases (2.9%). It was also higher in those who had dapsone monotherapy (1.92%) compared to those who had multidrug therapy (1.01%). The relapse rate was higher in the 10 to 29 years age group and among those who became pregnant suggesting puberty and pregnancy could be risk factors. Males had a significantly higher relapse rate (2.1%) than females (1.1%). 45.2% of relapses in N (Non-lepromatous) cases occurred within 24 months and 71.4% within 36 months of stopping treatment. In those having monotherapy, 57.1% of relapses occurred within 24 months and 76.8% within 36 months. Regularity in treatment did not seem to have much influence on relapse rates.

BT - Indian journal of leprosy C1 - http://www.ncbi.nlm.nih.gov/pubmed/1607715?dopt=Abstract CN - Infolep Library - available DA - 1992 Apr-Jun IS - 2 J2 - Indian J Lepr LA - eng N2 -

In this retrospective study of the 3737 cases of leprosy released from treatment and followed-up during 1975 to 1990, 63 had relapsed giving an overall relapse rate of 1.69%. The relapse rate was significantly higher in the immunologically unstable N?L (Borderline) cases (2.9%). It was also higher in those who had dapsone monotherapy (1.92%) compared to those who had multidrug therapy (1.01%). The relapse rate was higher in the 10 to 29 years age group and among those who became pregnant suggesting puberty and pregnancy could be risk factors. Males had a significantly higher relapse rate (2.1%) than females (1.1%). 45.2% of relapses in N (Non-lepromatous) cases occurred within 24 months and 71.4% within 36 months of stopping treatment. In those having monotherapy, 57.1% of relapses occurred within 24 months and 76.8% within 36 months. Regularity in treatment did not seem to have much influence on relapse rates.

PY - 1992 SP - 169 EP - 78 T2 - Indian journal of leprosy TI - Study of the characteristics and causes of relapse amongst leprosy cases in an urban area (Calcutta). VL - 64 SN - 0254-9395 ER -