TY - JOUR
KW - Azure Stains
KW - Biopsy, Fine-Needle
KW - Cytodiagnosis
KW - Diagnostic Errors
KW - Humans
KW - Leprosy, Borderline
KW - Leprosy, lepromatous
KW - Mycobacterium leprae
KW - Retrospective Studies
AU - Singh N
AU - Manucha V
AU - Bhattacharya S N
AU - Arora V
AU - Bhatia A
AB - <p>This is a blinded, retrospective, correlative study of classification of leprosy by cytomorphology, clinical examination, and bacterial density. One hundred consecutive adequate aspirates from skin lesions of leprosy were studied. The Ridley-Jopling (R-J) five-group classification system was used. May-Gruenwald-Giemsa (MGG) and Ziehl-Neelsen (Z-N) stains were employed. Complete clinical, cytological, and bacteriological concordance was found in 88 patients. One-step mismatch in classification was seen in 12 patients with cytomorphological features of borderline-borderline (BB/mid-borderline) leprosy. Cytomorphological features of BB leprosy in aspirates from skin lesions should alert the cytopathologist to the possibility that the bacteriological index (BI) may vary widely. Appropriate steps must be taken to ensure accurate reporting of BI.</p>
BT - Diagnostic cytopathology
C1 - http://www.ncbi.nlm.nih.gov/pubmed/15176024?dopt=Abstract
DA - 2004 Jun
DO - 10.1002/dc.20012
IS - 6
J2 - Diagn. Cytopathol.
LA - eng
N2 - <p>This is a blinded, retrospective, correlative study of classification of leprosy by cytomorphology, clinical examination, and bacterial density. One hundred consecutive adequate aspirates from skin lesions of leprosy were studied. The Ridley-Jopling (R-J) five-group classification system was used. May-Gruenwald-Giemsa (MGG) and Ziehl-Neelsen (Z-N) stains were employed. Complete clinical, cytological, and bacteriological concordance was found in 88 patients. One-step mismatch in classification was seen in 12 patients with cytomorphological features of borderline-borderline (BB/mid-borderline) leprosy. Cytomorphological features of BB leprosy in aspirates from skin lesions should alert the cytopathologist to the possibility that the bacteriological index (BI) may vary widely. Appropriate steps must be taken to ensure accurate reporting of BI.</p>
PY - 2004
SP - 386
EP - 8
T2 - Diagnostic cytopathology
TI - Pitfalls in the cytological classification of borderline leprosy in the Ridley-Jopling scale.
VL - 30
SN - 8755-1039
ER -