TY - JOUR KW - Animals KW - Bacterial Proteins KW - DNA, Bacterial KW - genotype KW - Humans KW - leprosy KW - Minisatellite Repeats KW - Mycobacterium leprae KW - polymerase chain reaction KW - Polymorphism, Genetic KW - Prevalence KW - Sigma Factor AU - Matsuoka M AU - Zhang L AB -
Application of molecular biological techniques to the epidemiological study of leprosy is described. Studies of detecting Mycobacterium leprae DNA in samples of the nasal mucus are discussed in terms of the epidemiology and the significance of high prevalence. Epidemiological studies on the transmission of leprosy and correlation between geographic distribution of different M. leprae rpoT genotypes and prehistoric spread of the leprosy by genotyping based on the genomic polymorphism are introduced.
BT - Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association C1 - http://www.ncbi.nlm.nih.gov/pubmed/15035063?dopt=Abstract DA - 2004 Feb IS - 1 J2 - Nihon Hansenbyo Gakkai Zasshi LA - jpn N2 -Application of molecular biological techniques to the epidemiological study of leprosy is described. Studies of detecting Mycobacterium leprae DNA in samples of the nasal mucus are discussed in terms of the epidemiology and the significance of high prevalence. Epidemiological studies on the transmission of leprosy and correlation between geographic distribution of different M. leprae rpoT genotypes and prehistoric spread of the leprosy by genotyping based on the genomic polymorphism are introduced.
PY - 2004 SP - 7 EP - 14 T2 - Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association TI - [Molecular epidemiology of the leprosy]. VL - 73 SN - 1342-3681 ER -