TY - JOUR KW - Animals KW - Bacterial Vaccines KW - BCG Vaccine KW - Disease Susceptibility KW - Dose-Response Relationship, Immunologic KW - Genetic Predisposition to Disease KW - Humans KW - Hypersensitivity, Delayed KW - Immunity, Cellular KW - Immunity, Innate KW - Leishmania tropica KW - Leishmaniasis, Cutaneous KW - leprosy KW - Mice KW - Mice, Inbred BALB C KW - Mycobacterium bovis KW - Mycobacterium leprae KW - Mycobacterium tuberculosis KW - Rats KW - Tuberculosis KW - Vaccination AU - Bretscher P A AB -

The pathogens responsible for leprosy, tuberculosis and the leishmaniases can induce different classes of immunity, but protection is provided only by a cell-mediated response. Here, Peter Bretscher proposes a strategy to achieve an immunological imprint that ensures a stable cell-mediated response upon natural infection.

BT - Immunology today C1 - http://www.ncbi.nlm.nih.gov/pubmed/1466750?dopt=Abstract DA - 1992 Sep DO - 10.1016/0167-5699(92)90168-7 IS - 9 J2 - Immunol. Today LA - eng N2 -

The pathogens responsible for leprosy, tuberculosis and the leishmaniases can induce different classes of immunity, but protection is provided only by a cell-mediated response. Here, Peter Bretscher proposes a strategy to achieve an immunological imprint that ensures a stable cell-mediated response upon natural infection.

PY - 1992 SP - 342 EP - 5 T2 - Immunology today TI - A strategy to improve the efficacy of vaccination against tuberculosis and leprosy. VL - 13 SN - 0167-5699 ER -