TY - JOUR
KW - Drug Therapy, Combination
KW - Follow-Up Studies
KW - Humans
KW - India
KW - Leprostatic Agents
KW - leprosy
KW - Mycobacterium leprae
KW - Secondary Prevention
KW - World Health Organization
AU - Desikan KV
AU - Sundaresh P
AU - Tulasidas I
AU - Rao PVR
AB - <p><b>OBJECTIVES: </b>To follow up highly bacillated leprosy patients for a long period after release from treatment (RFT) and to look out for possibility of relapses.</p><p><b>RESULTS: </b>660 patients with an initial bacterial positivity of 4 +, 5 + or 6 + who had undergone WHO multi-drug therapy and released from treatment, were followed up. The regularity of their treatment was kept high by close monitoring with home visits. They were reviewed twice, once 4 to 9 years after RFT and again 7 to 12 years after RFT. 516 patients were available in the second review. As per WHO definition, 5 patients were found to have relapsed, giving a relapse rate of 0.103 per 100 person years. This low relapse rate could be due to high regularity of treatment.</p><p><b>CONCLUSION: </b>With well supervised MDT and high regularity of treatment and proper consumption of drugs, relapse rate is very low.</p>
BT - Leprosy review
C1 - http://www.ncbi.nlm.nih.gov/pubmed/19009979?dopt=Abstract
CN - Infolep Library - available
DA - 2008 Sep
IS - 3
J2 - Lepr Rev
LA - eng
N2 - <p><b>OBJECTIVES: </b>To follow up highly bacillated leprosy patients for a long period after release from treatment (RFT) and to look out for possibility of relapses.</p><p><b>RESULTS: </b>660 patients with an initial bacterial positivity of 4 +, 5 + or 6 + who had undergone WHO multi-drug therapy and released from treatment, were followed up. The regularity of their treatment was kept high by close monitoring with home visits. They were reviewed twice, once 4 to 9 years after RFT and again 7 to 12 years after RFT. 516 patients were available in the second review. As per WHO definition, 5 patients were found to have relapsed, giving a relapse rate of 0.103 per 100 person years. This low relapse rate could be due to high regularity of treatment.</p><p><b>CONCLUSION: </b>With well supervised MDT and high regularity of treatment and proper consumption of drugs, relapse rate is very low.</p>
PY - 2008
SP - 303
EP - 10
T2 - Leprosy review
TI - An 8-12 year follow-up of highly bacillated Indian leprosy patients treated with WHO multi-drug therapy.
UR - https://leprosyreview.org/article/79/3/30-3310
VL - 79
SN - 0305-7518
ER -