TY - JOUR KW - Aged KW - Bolivia KW - Drug Therapy, Combination KW - Emigration and Immigration KW - Humans KW - Japan KW - Leprostatic Agents KW - leprosy KW - Male KW - Prednisolone KW - Treatment Outcome AU - Sugita Y AU - Yoshinaka M AU - Mukawa R AU - Oonuma S AU - Ishii N AU - Nakajima H AB -

We report a 74-year-old Japanese man who occurred leprosy at the age of 68. He moved to Bolivia at the age of 33 as an immigrant. He complained erythematous plaques on his trunk and extremeties and dysuria. Skin biopsy specimen revealed granulomatous lesions and acid fast staining showed numerous number of positively stained bacilli. He was diagnosed as multibacillary leprosy and MDT containing DDS, RFP, and CLF was started. During the treatment, he developed borderline reaction twice presenting severe pain and marked swelling on his hand and foot. The reaction was successfully treated with daily dose of 50 mg prednisolone combined with anti-leprosy drugs. SPFX, MINO, and CAM were not able to be used due to the side effects. One year has been passed after the stop of treatment without relapse.

BT - Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association C1 -

http://www.ncbi.nlm.nih.gov/pubmed/14598640?dopt=Abstract

DA - 2003 Aug IS - 3 J2 - Nihon Hansenbyo Gakkai Zasshi LA - jpn N2 -

We report a 74-year-old Japanese man who occurred leprosy at the age of 68. He moved to Bolivia at the age of 33 as an immigrant. He complained erythematous plaques on his trunk and extremeties and dysuria. Skin biopsy specimen revealed granulomatous lesions and acid fast staining showed numerous number of positively stained bacilli. He was diagnosed as multibacillary leprosy and MDT containing DDS, RFP, and CLF was started. During the treatment, he developed borderline reaction twice presenting severe pain and marked swelling on his hand and foot. The reaction was successfully treated with daily dose of 50 mg prednisolone combined with anti-leprosy drugs. SPFX, MINO, and CAM were not able to be used due to the side effects. One year has been passed after the stop of treatment without relapse.

PY - 2003 SP - 279 EP - 81 T2 - Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association TI - [A case of multibacillary leprosy]. VL - 72 SN - 1342-3681 ER -