TY - JOUR KW - Egypt KW - False Positive Reactions KW - Female KW - Humans KW - leprosy KW - Male KW - Syphilis KW - Syphilis Serodiagnosis KW - Tuberculosis AU - RUGE H AB -

In the course of a venereal disease survey in Egypt, 820 cases of leprosy and 720 cases of tuberculosis were serologically examined with the Wassermann, Meinicke (MKR II), and VDRL tests; the results are reported in this paper.On serological and anamnestic evidence, 31 cases of syphilis were discovered among the leprosy cases and 37 among the tuberculosis cases. Apparently false positive reactions were seen in 203 cases of leprosy (25%) and in 38 cases of tuberculosis (5%). The author discusses the probability that a fairly high proportion of these reactions were in fact caused by otherwise undetected syphilis or were non-specific.The Meinicke test proved the most specific of the three, followed, in that order, by the Wassermann and the VDRL tests.It was found that syphilis was more frequent among males with tuberculosis than among those with leprosy; this is attributed to the fact that leprosy patients are kept in greater isolation. Less easily explicable is the fact that more females than males with leprosy were found to have syphilis, whereas in tuberculous persons the difference in syphilis incidence between male and female patients was not very great.

BT - Bulletin of the World Health Organization C1 - http://www.ncbi.nlm.nih.gov/pubmed/13284561?dopt=Abstract DA - 1955 IS - 5 J2 - Bull. World Health Organ. LA - eng N2 -

In the course of a venereal disease survey in Egypt, 820 cases of leprosy and 720 cases of tuberculosis were serologically examined with the Wassermann, Meinicke (MKR II), and VDRL tests; the results are reported in this paper.On serological and anamnestic evidence, 31 cases of syphilis were discovered among the leprosy cases and 37 among the tuberculosis cases. Apparently false positive reactions were seen in 203 cases of leprosy (25%) and in 38 cases of tuberculosis (5%). The author discusses the probability that a fairly high proportion of these reactions were in fact caused by otherwise undetected syphilis or were non-specific.The Meinicke test proved the most specific of the three, followed, in that order, by the Wassermann and the VDRL tests.It was found that syphilis was more frequent among males with tuberculosis than among those with leprosy; this is attributed to the fact that leprosy patients are kept in greater isolation. Less easily explicable is the fact that more females than males with leprosy were found to have syphilis, whereas in tuberculous persons the difference in syphilis incidence between male and female patients was not very great.

PY - 1955 SP - 861 EP - 86 T2 - Bulletin of the World Health Organization TI - Serological findings in leprosy and tuberculosis with the Wassermann, Meinicke, and VDRL tests. UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538080/pdf/bullwho00544-0119.pdf VL - 13 SN - 0042-9686 ER -