TY - JOUR KW - Animals KW - Disease Models, Animal KW - Female KW - leprosy KW - Liver KW - Mice KW - Mice, Inbred BALB C KW - Mice, Inbred C57BL KW - Mycobacterium leprae KW - Spleen AU - Gangadharam P R AU - Dhople A M AB -
Dissemination of M. leprae to visceral organs is seen by four months onwards only in beige (C57BL/6/bgj) but not BALB/c mice following intravenous or intraperitoneal infections. Inoculation of the beige mouse derived M. leprae showed all the characteristics of M. leprae, including growth pattern in the foot-pads of BALB/c mice. M. leprae inoculated into foot-pads of beige mice multiplied faster than those in the foot-pads of BALB/c mice. The possibility of using beige mouse in chemotherapeutic studies in leprosy is discussed.
BT - Indian journal of leprosy C1 - http://www.ncbi.nlm.nih.gov/pubmed/1308522?dopt=Abstract CN - Infolep Library - available DA - 1992 Oct-Dec IS - 4 J2 - Indian J Lepr LA - eng N2 -Dissemination of M. leprae to visceral organs is seen by four months onwards only in beige (C57BL/6/bgj) but not BALB/c mice following intravenous or intraperitoneal infections. Inoculation of the beige mouse derived M. leprae showed all the characteristics of M. leprae, including growth pattern in the foot-pads of BALB/c mice. M. leprae inoculated into foot-pads of beige mice multiplied faster than those in the foot-pads of BALB/c mice. The possibility of using beige mouse in chemotherapeutic studies in leprosy is discussed.
PY - 1992 SP - 475 EP - 81 T2 - Indian journal of leprosy TI - Utility of beige mouse in leprosy research. VL - 64 SN - 0254-9395 ER -