A 40-year-old man, of Malian descent, born in France, presented with an urticarial rash, a positive antinuclear antibody titer, positive lupus anticoagulant and histological features consistent with systemic lupus erythematosus. Following treatment with systemic corticosteroids, the lesions resolved leaving hypopigmented plaques which were insensible to pain eventually. He subsequently developed a compressive ulnar mononeuropathy which insidiously evolved into a severe sensory and motor polyneuropathy with trophic skin changes. A nerve biopsy was indicative of borderline tuberculoïd leprosy. Treatment with multidrug therapy stopped the progression of the disease.
BT - Pratique Neurologique - FMC DO - 10.1016/j.praneu.2018.10.003 IS - 1 J2 - Pratique Neurologique - FMC LA - fre N2 -A 40-year-old man, of Malian descent, born in France, presented with an urticarial rash, a positive antinuclear antibody titer, positive lupus anticoagulant and histological features consistent with systemic lupus erythematosus. Following treatment with systemic corticosteroids, the lesions resolved leaving hypopigmented plaques which were insensible to pain eventually. He subsequently developed a compressive ulnar mononeuropathy which insidiously evolved into a severe sensory and motor polyneuropathy with trophic skin changes. A nerve biopsy was indicative of borderline tuberculoïd leprosy. Treatment with multidrug therapy stopped the progression of the disease.
PY - 2019 T2 - Pratique Neurologique - FMC TI - [Autochthonous leprosy exists in France: A diagnosis not to be missed] TT - La lèpre autochtone existe en France : un diagnostic à ne pas manquer VL - 10 SN - 18787762 ER -