TY - JOUR KW - Animals KW - Bacterial Vaccines KW - Cell Wall Skeleton KW - Female KW - leprosy KW - Mice KW - Mice, Inbred BALB C KW - Mycobacterium bovis KW - Mycobacterium leprae KW - Vaccination AU - Ngamying M AU - Sawanpanyalert P AU - Butraporn R AU - Nikasri J AU - Cho S AU - Levy L AU - Brennan PJ AB -
Only native products of Mycobacterium leprae, whether cell wall, cytosol, or membrane derived, can confer protective immunity against challenge in the mouse footpad. Previously, recombinant proteins were shown to be ineffective. The cell wall skeleton-the mycolyl-arabinogalactan-peptidoglycan complex-devoid of proteins is not protective.
BT - Infection and immunity C1 - http://www.ncbi.nlm.nih.gov/pubmed/12595485?dopt=Abstract DA - 2003 Mar DO - 10.1128/iai.71.3.1596-1598.2003 IS - 3 J2 - Infect. Immun. LA - eng N2 -Only native products of Mycobacterium leprae, whether cell wall, cytosol, or membrane derived, can confer protective immunity against challenge in the mouse footpad. Previously, recombinant proteins were shown to be ineffective. The cell wall skeleton-the mycolyl-arabinogalactan-peptidoglycan complex-devoid of proteins is not protective.
PY - 2003 SP - 1596 EP - 8 T2 - Infection and immunity TI - Effect of vaccination with refined components of the organism on infection of mice with Mycobacterium leprae. UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC148868/pdf/1297.pdf VL - 71 SN - 0019-9567 ER -