Nerve function impairment (NFI) commonly occurs during or after chemotherapy in leprosy. We previously described a clinical prediction rule to estimate the risk of NFI occurring within 2 years of diagnosis, based on 2510 patients who are followed up in the Bangladesh Acute Nerve Damage Study (BANDS). This prediction rule assigns new leprosy patients to one of three risk groups based on leprosy group and the presence or absence of NFI at registration. Updated data with up to 5 years of follow-up showed that 95% of all NFI occurred within 2 years. This study confirms the validity of the rule and supports the conclusion that there is little value for the detection of NFI in extending follow-up beyond 2 years.
BT - Leprosy review C1 - http://www.ncbi.nlm.nih.gov/pubmed/12669931?dopt=Abstract CN - CROFT 2003 DA - 2003 Mar IS - 1 J2 - Lepr Rev LA - eng N2 -Nerve function impairment (NFI) commonly occurs during or after chemotherapy in leprosy. We previously described a clinical prediction rule to estimate the risk of NFI occurring within 2 years of diagnosis, based on 2510 patients who are followed up in the Bangladesh Acute Nerve Damage Study (BANDS). This prediction rule assigns new leprosy patients to one of three risk groups based on leprosy group and the presence or absence of NFI at registration. Updated data with up to 5 years of follow-up showed that 95% of all NFI occurred within 2 years. This study confirms the validity of the rule and supports the conclusion that there is little value for the detection of NFI in extending follow-up beyond 2 years.
PY - 2003 SP - 35 EP - 41 T2 - Leprosy review TI - A clinical prediction rule for nerve function impairment in leprosy patients-revisited after 5 years of follow-up. UR - https://leprosyreview.org/article/74/1/03-541 VL - 74 SN - 0305-7518 ER -