TY - JOUR KW - China KW - False Positive Reactions KW - Humans KW - Immunity, Cellular KW - India KW - Japan KW - Kveim Test KW - Lepromin KW - leprosy KW - Malaysia KW - Skin Tests AU - Krishnamurthy S AU - Verghese R AU - Job C K AB -

The response to lepromin and Kveim antigens was compared and studied in 15 leprosy patients who were tuberculin negative. Of the 11 lepromin positive tuberculoid patients, 4 were Kveim positive, 1 was equivocal, and the rest were negative. Of the four lepromin negative lepromatous patients, one gave a positive Kveim test while the other three were negative. It has been shown that false-positive Kveim reactions are found in a higher percentage of South Indian leprosy patients than in those of other backgrounds, such as Japanese and Malaysian Chinese patients. It is also suggested that no definite relationship exists between the reaction of leprosy patients to lepromin and Kveim antigens. We further suggest that the anergy exhibited by lepromatous patients to the antigen of M. leprae is specific, as evidenced by the positive Kveim response in one lepromatous patient.

BT - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association C1 -

http://www.ncbi.nlm.nih.gov/pubmed/1241690?dopt=Abstract

DA - 1975 Oct-Dec IS - 4 J2 - Int. J. Lepr. Other Mycobact. Dis. LA - eng N2 -

The response to lepromin and Kveim antigens was compared and studied in 15 leprosy patients who were tuberculin negative. Of the 11 lepromin positive tuberculoid patients, 4 were Kveim positive, 1 was equivocal, and the rest were negative. Of the four lepromin negative lepromatous patients, one gave a positive Kveim test while the other three were negative. It has been shown that false-positive Kveim reactions are found in a higher percentage of South Indian leprosy patients than in those of other backgrounds, such as Japanese and Malaysian Chinese patients. It is also suggested that no definite relationship exists between the reaction of leprosy patients to lepromin and Kveim antigens. We further suggest that the anergy exhibited by lepromatous patients to the antigen of M. leprae is specific, as evidenced by the positive Kveim response in one lepromatous patient.

PY - 1975 SP - 333 EP - 8 T2 - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association TI - The Kveim test in leprosy. UR - http://ila.ilsl.br/pdfs/v43n4a06.pdf VL - 43 SN - 0148-916X ER -