TY - JOUR AU - MacRae C AU - Kopalakrishnan S AU - Faust L AU - Klowak M AU - Showler A AU - Klowak SA AU - Boggild AK AB -

Background: Leprosy is a potentially debilitating disease of the skin and nerves that requires a complex management approach consisting of laboratory monitoring, screening for factors that will adversely affect outcome with corticosteroids, engagement of allied health services, and prolonged follow-up. Given the complexities of leprosy management, a safety tool was developed and implemented in the Tropical Disease Unit at Toronto General Hospital. Our objective was to evaluate the utility of the tool using a retrospective chart review.

Methods: We reviewed the charts of patients with leprosy treated over a 3.5-year period: up to 3 years prior to tool implementation, and 6-months following implementation. Pre-determined outcomes of interest included: loss to follow-up; monitoring of laboratory parameters; allied health services engagement; baseline ophthalmologic assessment; and risk mitigation interventions.

Results: Of 17 patients enrolled, 8 were treated pre-implementation, and 9 post-implementation. Five (29.4%) pre-implementation patients were lost to follow-up compared to none post-implementation ( = 0.009). One (12.5%) pre-implementation patient was sent for baseline ophthalmologic assessment versus 8 (88.9%) post-implementation ( = 0.0034). Only post-implementation patients received referrals for occupational therapy and social work, with 77.8% ( = 7) receiving occupational therapy ( = 0.0023) and 33.3% ( = 3) social work ( = 0.2059). Laboratory parameters such as hemoglobin, hepatic transaminases, and methemoglobin were routinely monitored for patients on dapsone irrespective of tool implementation.

Conclusions: Implementation of a leprosy-specific safety tool has established a user-friendly method for systemizing all elements of care, and ensuring the involvement of allied health services necessary for optimizing health outcomes.

BT - Tropical diseases, travel medicine and vaccines C1 -

http://www.ncbi.nlm.nih.gov/pubmed/29507748?dopt=Abstract

DO - 10.1186/s40794-018-0061-9 J2 - Trop Dis Travel Med Vaccines LA - eng N2 -

Background: Leprosy is a potentially debilitating disease of the skin and nerves that requires a complex management approach consisting of laboratory monitoring, screening for factors that will adversely affect outcome with corticosteroids, engagement of allied health services, and prolonged follow-up. Given the complexities of leprosy management, a safety tool was developed and implemented in the Tropical Disease Unit at Toronto General Hospital. Our objective was to evaluate the utility of the tool using a retrospective chart review.

Methods: We reviewed the charts of patients with leprosy treated over a 3.5-year period: up to 3 years prior to tool implementation, and 6-months following implementation. Pre-determined outcomes of interest included: loss to follow-up; monitoring of laboratory parameters; allied health services engagement; baseline ophthalmologic assessment; and risk mitigation interventions.

Results: Of 17 patients enrolled, 8 were treated pre-implementation, and 9 post-implementation. Five (29.4%) pre-implementation patients were lost to follow-up compared to none post-implementation ( = 0.009). One (12.5%) pre-implementation patient was sent for baseline ophthalmologic assessment versus 8 (88.9%) post-implementation ( = 0.0034). Only post-implementation patients received referrals for occupational therapy and social work, with 77.8% ( = 7) receiving occupational therapy ( = 0.0023) and 33.3% ( = 3) social work ( = 0.2059). Laboratory parameters such as hemoglobin, hepatic transaminases, and methemoglobin were routinely monitored for patients on dapsone irrespective of tool implementation.

Conclusions: Implementation of a leprosy-specific safety tool has established a user-friendly method for systemizing all elements of care, and ensuring the involvement of allied health services necessary for optimizing health outcomes.

PY - 2018 EP - 1 T2 - Tropical diseases, travel medicine and vaccines TI - Evaluation of safety tool for ambulatory leprosy patients at risk of adverse outcome. UR - https://tdtmvjournal.biomedcentral.com/articles/10.1186/s40794-018-0061-9 VL - 4 SN - 2055-0936 ER -