TY - JOUR
KW - Drug Therapy, Combination
KW - Erythema Nodosum
KW - Humans
KW - Incidence
KW - Leprostatic Agents
KW - leprosy
KW - Leprosy, lepromatous
KW - Models, Molecular
KW - Mycobacterium leprae
KW - Thalidomide
KW - Tumor Necrosis Factor-alpha
AU - Teo SK
AU - Resztak K
AU - Scheffler MA
AU - Kook KA
AU - Zeldis JB
AU - Stirling DI
AU - Thomas S
AB - <p>Leprosy is a chronic infection of the skin and nerves caused by Mycobacterium leprae. Erythema nodosum leprosum (ENL) is a reactive state in lepromatous leprosy. Thalidomide has been used to treat ENL since the 1960s. One of its mechanisms of action is anti-inflammatory through selective inhibition of the pro-inflammatory cytokine TNF-alpha produced by monocytes.</p>
BT - Microbes and infection
C1 - http://www.ncbi.nlm.nih.gov/pubmed/12361920?dopt=Abstract
DA - 2002 Sep
IS - 11
J2 - Microbes Infect.
LA - eng
N2 - <p>Leprosy is a chronic infection of the skin and nerves caused by Mycobacterium leprae. Erythema nodosum leprosum (ENL) is a reactive state in lepromatous leprosy. Thalidomide has been used to treat ENL since the 1960s. One of its mechanisms of action is anti-inflammatory through selective inhibition of the pro-inflammatory cytokine TNF-alpha produced by monocytes.</p>
PY - 2002
SP - 1193
EP - 202
T2 - Microbes and infection
TI - Thalidomide in the treatment of leprosy.
VL - 4
SN - 1286-4579
ER -