The primary aim of this study was to study the relapse rate in the post-elimination phase of leprosy and the secondary aim to study the clinical features of the relapsed cases in a Tertiary Care Centre in Thiruvanthapuram, South India. This was a 10 year retrospective study of relapsed cases of leprosy in the post-elimination phase. There were 39 cases of relapse in the 10 year (2006-2015) study period, with a relapse rate of 10.03%. Out of 39 relapses, 8 were PB cases and31 were MB cases. There were 33 males (84.61%) and 6 females (15.39%) with a male/female ratio of 5.5:1. The mean age was 46.82 years and age group 41-50 constituted the maximum number of cases 11 (28.21%). Borderline tuberculoid (BT) was the commonest initial type of leprosy to relapse, 17 cases (43.58%), while the commonest type in the relapsed state was also BT, 18 cases (46.15%). BT relapsing as BT was the commonest type, 13 cases (33.33%). Relapse was more common in smear positive cases, 21 (53.85%), compared to smear negative cases, 18 (46.15%). Twelve (12/21, 57.14%) relapses in smear positive cases (BI 4+) were in those who were treated with FDT for one year. This study shows a high prevalence of relapse cases in the post-elimination phase in cases treated in a tertiary care settings which indicates the need of in-depth studies to find out determinants such as subsets of cases at higher risk of getting relapse and duration of treatment in such cases as well as long term steroids.
BT - Indian journal of leprosy J2 - Indian J Lepr LA - eng N2 -The primary aim of this study was to study the relapse rate in the post-elimination phase of leprosy and the secondary aim to study the clinical features of the relapsed cases in a Tertiary Care Centre in Thiruvanthapuram, South India. This was a 10 year retrospective study of relapsed cases of leprosy in the post-elimination phase. There were 39 cases of relapse in the 10 year (2006-2015) study period, with a relapse rate of 10.03%. Out of 39 relapses, 8 were PB cases and31 were MB cases. There were 33 males (84.61%) and 6 females (15.39%) with a male/female ratio of 5.5:1. The mean age was 46.82 years and age group 41-50 constituted the maximum number of cases 11 (28.21%). Borderline tuberculoid (BT) was the commonest initial type of leprosy to relapse, 17 cases (43.58%), while the commonest type in the relapsed state was also BT, 18 cases (46.15%). BT relapsing as BT was the commonest type, 13 cases (33.33%). Relapse was more common in smear positive cases, 21 (53.85%), compared to smear negative cases, 18 (46.15%). Twelve (12/21, 57.14%) relapses in smear positive cases (BI 4+) were in those who were treated with FDT for one year. This study shows a high prevalence of relapse cases in the post-elimination phase in cases treated in a tertiary care settings which indicates the need of in-depth studies to find out determinants such as subsets of cases at higher risk of getting relapse and duration of treatment in such cases as well as long term steroids.
PY - 2017 SP - 119 EP - 125 T2 - Indian journal of leprosy TI - Relapse in leprosy in post-elimination phase: Scenario from a tertiary care center in South India. UR - http://www.ijl.org.in/2017/1%20S%20Pradeep%20Nair%20(119-125).pdf VL - 89 ER -