TY - JOUR
KW - leprosy
KW - Mast Cells
KW - Metachromatic
KW - Lepromatous
KW - Tuberculoid
AU - Jindal S
AU - Manjari M
AU - Girdhar M
AB - <p><strong>BACKGROUND</strong></p>

<p>Mast cells have received little attention in leprosy, but evidence linking them with delayed-type hypersensitivity reactions raises the possibility that they may be of some importance in leprosy.</p>

<p><strong>MATERIALS AND METHODS</strong></p>

<p>The present study is a descriptive study. Biopsies obtained from the clinically diagnosed patients were fixed in 10% formalin, processed and three sections of 6 µm thickness were cut and stained with routine Haematoxylin and Eosin (Culling, Allison, Barr 1985), by Toluidine Blue and by Modified Thionin/Acridine Orange method.</p>

<p><strong>RESULTS</strong></p>

<p>Mean number of mast cells were more in lepromatous leprosy than in tuberculoid.</p>

<p><strong>CONCLUSION</strong></p>

<p>This study reflects the variety of immunological reactions occurring in leprosy and the role of mast cells in these immunological phenomena.</p>

BT - Journal of evolution of medical and dental sciences
DO - 10.14260/jemds10.14260/Jemds/2017/1157
IS - 75
LA - eng
N2 - <p><strong>BACKGROUND</strong></p>

<p>Mast cells have received little attention in leprosy, but evidence linking them with delayed-type hypersensitivity reactions raises the possibility that they may be of some importance in leprosy.</p>

<p><strong>MATERIALS AND METHODS</strong></p>

<p>The present study is a descriptive study. Biopsies obtained from the clinically diagnosed patients were fixed in 10% formalin, processed and three sections of 6 µm thickness were cut and stained with routine Haematoxylin and Eosin (Culling, Allison, Barr 1985), by Toluidine Blue and by Modified Thionin/Acridine Orange method.</p>

<p><strong>RESULTS</strong></p>

<p>Mean number of mast cells were more in lepromatous leprosy than in tuberculoid.</p>

<p><strong>CONCLUSION</strong></p>

<p>This study reflects the variety of immunological reactions occurring in leprosy and the role of mast cells in these immunological phenomena.</p>

PY - 2017
SP - 5328
EP - 5331
ST - jemds
T2 - Journal of evolution of medical and dental sciences
TI - Role of mast cells in leprosy- A study of 62 cases.
UR - https://www.jemds.com/data_pdf/shivani%20jindal-%20--sept%2018-.pdf
VL - 6
SN - 22784748
ER -