Histoid leprosy is an uncommon variant of lepromatous leprosy with characteristic clinical, immunologic and bacteriologic findings. It usually manifests as relapse in lepromatous patients who are on dapsone monotherapy but uncommonly also arises de-novo. We report a case of de-novo Histoid Leprosy clinically mimicking as Cryptococcosis. Our patient mimicked cutaneous cryptococcosis because of disseminated lesions which were umblicated with central ulceration and crusting, along with firm papules. Characteristic histopathological findings, presence of mycobacteria in slit skin smears, and nerve thickening helped in arriving at diagnosis of histoid leprosy and these markers/ features should be considered for differentiating these two conditions.
BT - Indian journal of leprosy J2 - Indian J Lepr LA - eng N2 -Histoid leprosy is an uncommon variant of lepromatous leprosy with characteristic clinical, immunologic and bacteriologic findings. It usually manifests as relapse in lepromatous patients who are on dapsone monotherapy but uncommonly also arises de-novo. We report a case of de-novo Histoid Leprosy clinically mimicking as Cryptococcosis. Our patient mimicked cutaneous cryptococcosis because of disseminated lesions which were umblicated with central ulceration and crusting, along with firm papules. Characteristic histopathological findings, presence of mycobacteria in slit skin smears, and nerve thickening helped in arriving at diagnosis of histoid leprosy and these markers/ features should be considered for differentiating these two conditions.
PY - 2017 SP - 45 EP - 48 T2 - Indian journal of leprosy TI - De-novo Histoid Leprosy Masquerading as Cryptococcosis: A Case Report UR - http://www.ijl.org.in/2017/7%20DK%20Meena1%20et%20al%20(45-48).pdf VL - 89 ER -