BACKGROUND: Non-healing trophic ulcers in Hansen's disease patients is one of the major causes for disability. It has been shown that autologous platelet-rich fibrin matrix (PRFM) is effective in healing chronic non-healing leg ulcers.
AIM: The objective of this study is to demonstrate the efficacy of autologous platelet-rich fibrin matrix (PRFM) in non-healing trophic ulcers in patients treated for Hansen's disease.
DESIGN: A prospective study.
SETTING: An institution-based clinic.
PARTICIPANTS: Seven treated patients with Hansen's disease, with a mean age of 38.33 years, with nine non-healing trophic ulcer of more than 6 weeks duration.
MEASUREMENTS: Photographs were taken before treatment and at every subsequent sitting. Area and volume were calculated at baseline and every subsequent sitting till the closure was achieved.
MATERIALS AND METHODS: The healthy ulcers were treated with PRFM at weekly intervals, repeated once a week for a maximum of five sittings as per requirement.
RESULTS: The mean percentage improvement in the area was 93.52%, and volume was 97.74% at the end of the second sitting. All ulcers closed by a maximum of five sittings. No adverse events were noted.
CONCLUSION: PRFM for the treatment of trophic ulcers in treated patients with Hansen's disease is a feasible, safe, simple and inexpensive method.
BT - Journal of cutaneous and aesthetic surgery C1 -http://www.ncbi.nlm.nih.gov/pubmed/28529413?dopt=Abstract
DO - 10.4103/JCAS.JCAS_17_16 IS - 1 J2 - J Cutan Aesthet Surg LA - eng N2 -BACKGROUND: Non-healing trophic ulcers in Hansen's disease patients is one of the major causes for disability. It has been shown that autologous platelet-rich fibrin matrix (PRFM) is effective in healing chronic non-healing leg ulcers.
AIM: The objective of this study is to demonstrate the efficacy of autologous platelet-rich fibrin matrix (PRFM) in non-healing trophic ulcers in patients treated for Hansen's disease.
DESIGN: A prospective study.
SETTING: An institution-based clinic.
PARTICIPANTS: Seven treated patients with Hansen's disease, with a mean age of 38.33 years, with nine non-healing trophic ulcer of more than 6 weeks duration.
MEASUREMENTS: Photographs were taken before treatment and at every subsequent sitting. Area and volume were calculated at baseline and every subsequent sitting till the closure was achieved.
MATERIALS AND METHODS: The healthy ulcers were treated with PRFM at weekly intervals, repeated once a week for a maximum of five sittings as per requirement.
RESULTS: The mean percentage improvement in the area was 93.52%, and volume was 97.74% at the end of the second sitting. All ulcers closed by a maximum of five sittings. No adverse events were noted.
CONCLUSION: PRFM for the treatment of trophic ulcers in treated patients with Hansen's disease is a feasible, safe, simple and inexpensive method.
PY - 2017 SP - 3 EP - 7 T2 - Journal of cutaneous and aesthetic surgery TI - Autologous Platelet-rich Fibrin Matrix in Non-healing Trophic Ulcers in Patients with Hansen's Disease. UR - http://www.jcasonline.com/article.asp?issn=0974-2077;year=2017;volume=10;issue=1;spage=3;epage=7;aulast=Nagaraju VL - 10 SN - 0974-2077 ER -