TY - JOUR
KW - Anti-Bacterial Agents
KW - Clofazimine
KW - Dapsone
KW - Dose-Response Relationship, Drug
KW - Drug Administration Schedule
KW - Drug Resistance, Bacterial
KW - Drug Therapy, Combination
KW - Female
KW - Humans
KW - Leprostatic Agents
KW - leprosy
KW - Male
KW - Mycobacterium leprae
KW - Prognosis
KW - Rifampin
KW - Risk Assessment
KW - Treatment Outcome
KW - World Health Organization
AU - Kar HK
AU - Gupta R
AB - <p>Leprosy is a curable disease, having been eliminated from many countries, including India. This has been possible due to the wide availability of effective and safe drugs. Treatment of leprosy has undergone considerable changes over decades, from chaulmoogra oil in 1915 to dapsone monotherapy in 1946, then eventually to multidrug therapy (MDT) in 1982. In the last two decades, reports of resistance to all first-line drugs have appeared in the literature, with the need to conduct clinical trials using newer but highly bactericidal drugs and their combinations against Mycobacterium leprae.</p>

BT - Clinics in dermatology
C1 - <p>http://www.ncbi.nlm.nih.gov/pubmed/25432811?dopt=Abstract</p>

DO - 10.1016/j.clindermatol.2014.07.007
IS - 1
J2 - Clin. Dermatol.
LA - eng
N2 - <p>Leprosy is a curable disease, having been eliminated from many countries, including India. This has been possible due to the wide availability of effective and safe drugs. Treatment of leprosy has undergone considerable changes over decades, from chaulmoogra oil in 1915 to dapsone monotherapy in 1946, then eventually to multidrug therapy (MDT) in 1982. In the last two decades, reports of resistance to all first-line drugs have appeared in the literature, with the need to conduct clinical trials using newer but highly bactericidal drugs and their combinations against Mycobacterium leprae.</p>

PY - 2015
SP - 55
EP - 65
T2 - Clinics in dermatology
TI - Treatment of leprosy.
VL - 33
SN - 1879-1131
ER -