TY - JOUR KW - Adolescent KW - Adult KW - Age Factors KW - Child KW - China KW - Communicable Disease Control KW - Dapsone KW - Disability Evaluation KW - Drug Therapy, Combination KW - Humans KW - Incidence KW - Leprostatic Agents KW - leprosy KW - Recurrence AU - Shen J AU - Gupte M D AU - Jiang C AU - Manickam P AU - Yu M AU - Li W AB -
OBJECTIVE: To analyze the trends of case detection and other indicators of leprosy in China during 1985-2002.
METHODS: Data reported by each province were collected by China National Leprosy Database in Nanjing P.R. China. All data about registered cases were put into computer for analysis.
RESULTS: From 1985 to 2002, a total of 49,477 new leprosy cases had been detected. Among them, 69.5% were multibacillary cases and 25.4% had grade 2 disability. The child cases aged below 15 years accounted for 3.74% of total cases. Totally, 5824 cases and 303 cases relapsed after dapsone (DDS) mono-therapy and multidrug therapy (MDT), respectively. Case detection showed a marked reduction from 0.47/100,000 in 1985 to 0.18/100,000 in 1993 although there were several spurts due to operational factors. From 1994, case detection showed no significant decline. The grade 2 disability among new patients decreased from 31.4% in 1985 to 23.4% in 2002. The child case detection rate among new cases fluctuated between 2.70%-3.56% from 1999 to 2002. The incidence of relapse declined after the introduction of DDS mono-therapy. However, it increased after the introduction of MDT.
CONCLUSION: China experiences in leprosy control show that it will take a long time with continuing present leprosy control activities to bring down the case detection and other indicators to a very low level even after reaching the elimination goal of leprosy.
BT - Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih C1 - http://www.ncbi.nlm.nih.gov/pubmed/16075742?dopt=Abstract CN - SHEN2005 DA - 2005 Jun IS - 2 J2 - Chin. Med. Sci. J. LA - eng N2 -OBJECTIVE: To analyze the trends of case detection and other indicators of leprosy in China during 1985-2002.
METHODS: Data reported by each province were collected by China National Leprosy Database in Nanjing P.R. China. All data about registered cases were put into computer for analysis.
RESULTS: From 1985 to 2002, a total of 49,477 new leprosy cases had been detected. Among them, 69.5% were multibacillary cases and 25.4% had grade 2 disability. The child cases aged below 15 years accounted for 3.74% of total cases. Totally, 5824 cases and 303 cases relapsed after dapsone (DDS) mono-therapy and multidrug therapy (MDT), respectively. Case detection showed a marked reduction from 0.47/100,000 in 1985 to 0.18/100,000 in 1993 although there were several spurts due to operational factors. From 1994, case detection showed no significant decline. The grade 2 disability among new patients decreased from 31.4% in 1985 to 23.4% in 2002. The child case detection rate among new cases fluctuated between 2.70%-3.56% from 1999 to 2002. The incidence of relapse declined after the introduction of DDS mono-therapy. However, it increased after the introduction of MDT.
CONCLUSION: China experiences in leprosy control show that it will take a long time with continuing present leprosy control activities to bring down the case detection and other indicators to a very low level even after reaching the elimination goal of leprosy.
PY - 2005 SP - 77 EP - 82 T2 - Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih TI - Trends of case detection and other indicators of leprosy in China during 1985-2002. VL - 20 SN - 1001-9294 ER -