TY - JOUR KW - Saliva KW - Reactional episodes KW - Oral cavity KW - Mycobacterium leprae KW - leprosy KW - Immunology AU - Rodrigues GA AU - QUALIO NP AU - Macedo LD AU - Innocentini LMAR AU - Ribeiro-Silva A AU - Foss N AU - Cipriani Frade M AU - Motta AC AB -

Leprosy is a chronic infectious disease caused by Mycobacterium leprae, a bacillus that has a tropism for skin and peripheral nerves. Leprosy treatment is based on a multidrug therapy established by the World Health Organization in 1982 and, despite its widespread use, Brazil ranks second worldwide in numbers of cases. Oral involvement in leprosy has been poorly described in the literature, and few studies have shown that although the bacillus is found in mucosa, specific leprosy lesions are rare and affect patients with advanced stages of the disease. This review aimed to assess the literature on oral manifestations in leprosy and the aspects involving oral cavity in leprosy pathogenesis. This article is protected by copyright. All rights reserved.

BT - Oral diseases C1 -

http://www.ncbi.nlm.nih.gov/pubmed/27606832?dopt=Abstract

DO - 10.1111/odi.12582 J2 - Oral Dis LA - eng N2 -

Leprosy is a chronic infectious disease caused by Mycobacterium leprae, a bacillus that has a tropism for skin and peripheral nerves. Leprosy treatment is based on a multidrug therapy established by the World Health Organization in 1982 and, despite its widespread use, Brazil ranks second worldwide in numbers of cases. Oral involvement in leprosy has been poorly described in the literature, and few studies have shown that although the bacillus is found in mucosa, specific leprosy lesions are rare and affect patients with advanced stages of the disease. This review aimed to assess the literature on oral manifestations in leprosy and the aspects involving oral cavity in leprosy pathogenesis. This article is protected by copyright. All rights reserved.

PY - 2016 T2 - Oral diseases TI - The oral cavity in leprosy: what clinicians need to know. SN - 1601-0825 ER -