TY - JOUR
KW - Animals
KW - Anti-Inflammatory Agents
KW - Dapsone
KW - Drug Combinations
KW - Horseradish Peroxidase
KW - Leprostatic Agents
KW - leprosy
KW - Liver
KW - Mice
KW - Mice, Inbred CBA
KW - Neutrophils
KW - Peroxidase
KW - Phagocytes
KW - Rifampin
KW - Time Factors
AU - Maslov A K
AU - Luzhnova S A
AU - Kalyanina O V
AB - <p>Therapeutic effect of lyophilized horseradish peroxidase in complex with the basic antileprosy drugs diaminodiphenylsulfone and rifampicin was studied in experimental leprosy. Oral therapy with drug complexes was more effective than monotherapy. Treatment with drug combinations activated myeloperoxidase in blood neutrophil, produced an antiinflammatory effect, stimulated cell immunity, and had no toxic effect on mouse liver.</p>
BT - Bulletin of experimental biology and medicine
C1 - http://www.ncbi.nlm.nih.gov/pubmed/11865328?dopt=Abstract
DA - 2001 Nov
DO - 10.1023/a:1017924826491
IS - 5
J2 - Bull. Exp. Biol. Med.
LA - eng
N2 - <p>Therapeutic effect of lyophilized horseradish peroxidase in complex with the basic antileprosy drugs diaminodiphenylsulfone and rifampicin was studied in experimental leprosy. Oral therapy with drug complexes was more effective than monotherapy. Treatment with drug combinations activated myeloperoxidase in blood neutrophil, produced an antiinflammatory effect, stimulated cell immunity, and had no toxic effect on mouse liver.</p>
PY - 2001
SP - 1084
EP - 6
T2 - Bulletin of experimental biology and medicine
TI - Effect of peroxidase in complex with basic antileprosy drugs on liver, blood, and functional activity of phagocytes in mice with experimental leprosy.
VL - 132
SN - 0007-4888
ER -