O-diphenoloxidase activity was studied in 15 patients with lepromatous leprosy, 15 with tuberculois leprosy, and 15 controls. O-diphenoloxidase isolated from skin and serum samples of patients with lepromatous leprosy had the specificity of a bacterially derived enzyme and not that of a mammalian-derived enzyme. Only the patients who had lepromatous leprosy for over two years showed enzyme activity in serum, though all showed it in skin tissue. O-diphenoloxidase activity in serum may be a useful diagnostic marker of lepromatous leprosy.
BT - British medical journal C1 - http://www.ncbi.nlm.nih.gov/pubmed/117872?dopt=Abstract DA - 1979 Oct 13 DO - 10.1136/bmj.2.6195.900 IS - 6195 J2 - Br Med J LA - eng N2 -O-diphenoloxidase activity was studied in 15 patients with lepromatous leprosy, 15 with tuberculois leprosy, and 15 controls. O-diphenoloxidase isolated from skin and serum samples of patients with lepromatous leprosy had the specificity of a bacterially derived enzyme and not that of a mammalian-derived enzyme. Only the patients who had lepromatous leprosy for over two years showed enzyme activity in serum, though all showed it in skin tissue. O-diphenoloxidase activity in serum may be a useful diagnostic marker of lepromatous leprosy.
PY - 1979 SP - 900 EP - 1 T2 - British medical journal TI - O-diphenoloxidase concentrations in leprosy. VL - 2 SN - 0007-1447 ER -