TY - JOUR
KW - Animals
KW - Anti-Infective Agents
KW - Antibiotics, Antitubercular
KW - Base Sequence
KW - DNA Primers
KW - DNA, Bacterial
KW - Drug Resistance, Microbial
KW - Drug Resistance, Multiple
KW - Genes, Bacterial
KW - Humans
KW - Leprostatic Agents
KW - leprosy
KW - Mice
KW - Molecular Sequence Data
KW - Mycobacterium leprae
KW - Ofloxacin
KW - Reverse Transcriptase Polymerase Chain Reaction
KW - Rifampin
AU - Maeda S
AU - Matsuoka M
AU - Nakata N
AU - Kai M
AU - Maeda Y
AU - Hashimoto K
AU - Kimura H
AU - Kobayashi K
AU - Kashiwabara Y
AB - <p>Sequences of the folP1, rpoB, and gyrA genes were analyzed for 88 isolates of Mycobacterium leprae from leprosy patients in Japan, Haiti, Indonesia, Pakistan, and the Philippines. Thirteen isolates (14.8%) showed representative mutations in more than two genes, suggesting the emergence of multidrug-resistant M. leprae.</p>
BT - Antimicrobial agents and chemotherapy
C1 - http://www.ncbi.nlm.nih.gov/pubmed/11709358?dopt=Abstract
CN - MAEDA 2001
DA - 2001 Dec
DO - 10.1128/AAC.45.12.3635-3639.2001
IS - 12
J2 - Antimicrob. Agents Chemother.
LA - eng
N2 - <p>Sequences of the folP1, rpoB, and gyrA genes were analyzed for 88 isolates of Mycobacterium leprae from leprosy patients in Japan, Haiti, Indonesia, Pakistan, and the Philippines. Thirteen isolates (14.8%) showed representative mutations in more than two genes, suggesting the emergence of multidrug-resistant M. leprae.</p>
PY - 2001
SP - 3635
EP - 9
T2 - Antimicrobial agents and chemotherapy
TI - Multidrug resistant Mycobacterium leprae from patients with leprosy.
VL - 45
SN - 0066-4804
ER -