TY - JOUR KW - Vaccination KW - Male KW - Malawi KW - leprosy KW - Infant, Newborn KW - Infant KW - Humans KW - Female KW - Evaluation Studies as Topic KW - Child, Preschool KW - Child KW - BCG Vaccine KW - Adult KW - Adolescent AU - Fine PE AU - Ponnighaus J M AU - Maine N AU - Clarkson J A AU - Bliss L AB -

The effectiveness of a BCG vaccination programme in protecting against leprosy was assessed by case-control and cohort analyses of data from the Lepra Evaluation Project in Karonga District, Northern Malawi. Results indicate that BCG provides at least 50% protection against leprosy in this population and that protection is independent of age, sex, schooling status, or location within the project area. Agreement between these findings and those from a controlled trial in Uganda indicates that BCG is sufficiently effective against leprosy in East and Central Africa to be considered an important element of leprosy control in that region.

BT - Lancet C1 - http://www.ncbi.nlm.nih.gov/pubmed/2875247?dopt=Abstract DA - 1986 Aug 30 IS - 8505 J2 - Lancet LA - eng N2 -

The effectiveness of a BCG vaccination programme in protecting against leprosy was assessed by case-control and cohort analyses of data from the Lepra Evaluation Project in Karonga District, Northern Malawi. Results indicate that BCG provides at least 50% protection against leprosy in this population and that protection is independent of age, sex, schooling status, or location within the project area. Agreement between these findings and those from a controlled trial in Uganda indicates that BCG is sufficiently effective against leprosy in East and Central Africa to be considered an important element of leprosy control in that region.

PY - 1986 SP - 499 EP - 502 T2 - Lancet TI - Protective efficacy of BCG against leprosy in Northern Malawi. UR - http://www.med.mcgill.ca/epidemiology/Hanley/bios601/CaseControlStudies/FineEtAlBCGleprosy.pdf VL - 2 SN - 0140-6736 ER -