TY - JOUR
KW - Steroids
KW - Neuritis
KW - Middle Aged
KW - Male
KW - leprosy
KW - Humans
KW - HIV Infections
KW - Female
KW - Child
KW - Aged
KW - Adult
KW - Adolescent
AU - Bwire R
AU - Kawuma H J
AB - <p>The incidence of type 1 reactions and neuritis among HIV seronegative and HIV seropositive leprosy patients was investigated. HIV seropositivity was associated with an increased incidence of type 1 reactions among multibacillary (MB) patients, which were observed in 9 of 12 seropositive MB patients and in 8 of 40 HIV seronegative MB patients (P < 0.0005). Similarly, the incidence of neuritis was significantly increased among the HIV seropositive MB patients, of whom 8 developed acute neuritis compared to 3 of the HIV seronegative patients (P < 0.0005). There was no significant difference between the numbers of paucibacillary HIV seropositive and HIV seronegative patients who developed these complications. Both the HIV seronegative and HIV seropositive patients showed a similar response to steroid therapy for the management of acute neuritis.</p>
BT - Trans R Soc Trop Med Hyg
C1 - http://www.ncbi.nlm.nih.gov/pubmed/7974675?dopt=Abstract
DA - 1994 May-Jun
IS - 3
J2 - Trans. R. Soc. Trop. Med. Hyg.
LA - eng
N2 - <p>The incidence of type 1 reactions and neuritis among HIV seronegative and HIV seropositive leprosy patients was investigated. HIV seropositivity was associated with an increased incidence of type 1 reactions among multibacillary (MB) patients, which were observed in 9 of 12 seropositive MB patients and in 8 of 40 HIV seronegative MB patients (P < 0.0005). Similarly, the incidence of neuritis was significantly increased among the HIV seropositive MB patients, of whom 8 developed acute neuritis compared to 3 of the HIV seronegative patients (P < 0.0005). There was no significant difference between the numbers of paucibacillary HIV seropositive and HIV seronegative patients who developed these complications. Both the HIV seronegative and HIV seropositive patients showed a similar response to steroid therapy for the management of acute neuritis.</p>
PY - 1994
SP - 315
EP - 6
T2 - Trans R Soc Trop Med Hyg
TI - Type 1 reactions in leprosy, neuritis and steroid therapy: the impact of the human immunodeficiency virus.
VL - 88
SN - 0035-9203
ER -