Objectives: To evaluate PSA (Prostate-specific antigen) parameters in patients with lepromatous leprosy (LL). Design: In a retrospective study, 23 male patients with LL were evaluated. PSA parameters (serum total PSA (tPSA), free PSA fPSA), free-to-total PSA ratio (f/tPSA), PSA Density (PSAD)) were assessed. PSA parameters were compared with a control group. Conclusions: Serum tPSA values and prostate volumes in the patients with LL were significantly reduced and f/tPSA values were significantly increased. Testicular atrophy in the lepromatous cases might be due to leprosy-related orchitis and associated with a reduction in prostatic volume.
BT - Leprosy review C1 -http://www.ncbi.nlm.nih.gov/pubmed/24974442
IS - 1 J2 - Lep Rev LA - eng N2 -Objectives: To evaluate PSA (Prostate-specific antigen) parameters in patients with lepromatous leprosy (LL). Design: In a retrospective study, 23 male patients with LL were evaluated. PSA parameters (serum total PSA (tPSA), free PSA fPSA), free-to-total PSA ratio (f/tPSA), PSA Density (PSAD)) were assessed. PSA parameters were compared with a control group. Conclusions: Serum tPSA values and prostate volumes in the patients with LL were significantly reduced and f/tPSA values were significantly increased. Testicular atrophy in the lepromatous cases might be due to leprosy-related orchitis and associated with a reduction in prostatic volume.
PY - 2014 SP - 48 EP - 53 T2 - Leprosy review TI - Prostatic and testicular parameters in lepromatous patients UR - https://leprosyreview.org/article/85/1/00-1846 VL - 85 ER -