TY - JOUR KW - Administration, Topical KW - Adult KW - Aged KW - Female KW - Humans KW - Ketanserin KW - leprosy KW - Male KW - Middle Aged KW - Serotonin Antagonists KW - Skin Ulcer KW - Treatment Outcome AU - Salazar J J AU - Serrano G G AU - Leon-Quintero G I AU - Torres-Mendoza B M AB -

A comparative study was carried out in which 66 leprosy patients with ulcers were randomly divided in two groups of 33 patients each: Group A (experimental group) was treated with ketanserin gel (2%) and group B with clioquinol cream and/or Lassar paste during a three month period. At the end of the study, when ulcer sizes in the two groups were compared, the group treated with topical ketanserin showed superior results (p < 0.001 using Kolmogorov-Smirnov's test). We conclude that the drug is useful as coadjuavant treatment for healing ulcers in these patients.

BT - Indian journal of leprosy C1 - http://www.ncbi.nlm.nih.gov/pubmed/11579646?dopt=Abstract CN - Infolep Library - available DA - 2001 Apr-Jun IS - 2 J2 - Indian J Lepr LA - eng N2 -

A comparative study was carried out in which 66 leprosy patients with ulcers were randomly divided in two groups of 33 patients each: Group A (experimental group) was treated with ketanserin gel (2%) and group B with clioquinol cream and/or Lassar paste during a three month period. At the end of the study, when ulcer sizes in the two groups were compared, the group treated with topical ketanserin showed superior results (p < 0.001 using Kolmogorov-Smirnov's test). We conclude that the drug is useful as coadjuavant treatment for healing ulcers in these patients.

PY - 2001 SP - 103 EP - 10 T2 - Indian journal of leprosy TI - Use of topical ketanserin for the treatment of ulcers in leprosy patients. VL - 73 SN - 0254-9395 ER -