TY - JOUR
KW - Multi drug therapy
KW - leprosy
KW - Enteropathy
KW - Clofazimine
AU - Singh H
AU - Azad K
AU - Kaur K
AB - Clofazimine-induced crystal-storing histiocytosis is a rare but well-recognized condition reported in literature. In addition to common reddish discoloration of the skin, clofazimine produces gastrointestinal disorder, sometimes severe abdominal pain. Also, the pathologic and radiologic findings can produce diagnostic difficulties if the pathological changes caused by it are not known. The authors report a case in a patient of leprosy to emphasize the importance of history, radiologic, and pathologic findings in small intestine. Clofazimine crystals are red in the frozen section and display bright-red birefringence. With the knowledge of this rare condition caused by clofazimine, appropriate management to avoid an unnecessary laparotomy is possible.

BT - Indian Journal of Pharmacology
C1 - http://www.ncbi.nlm.nih.gov/pubmed/23716903 
DO - http://www.ijp-online.com/text.asp?2013/45/2/197/108323
IS - 2
J2 - Indian J Pharmacol 
LA - eng
N2 - Clofazimine-induced crystal-storing histiocytosis is a rare but well-recognized condition reported in literature. In addition to common reddish discoloration of the skin, clofazimine produces gastrointestinal disorder, sometimes severe abdominal pain. Also, the pathologic and radiologic findings can produce diagnostic difficulties if the pathological changes caused by it are not known. The authors report a case in a patient of leprosy to emphasize the importance of history, radiologic, and pathologic findings in small intestine. Clofazimine crystals are red in the frozen section and display bright-red birefringence. With the knowledge of this rare condition caused by clofazimine, appropriate management to avoid an unnecessary laparotomy is possible.

PY - 2013
SP - 197
EP - 198
T2 - Indian Journal of Pharmacology
TI - Clofazimine-induced enteropathy in a patient of leprosy
UR - http://ijp-online.com/article.asp?issn=0253-7613;year=2013;volume=45;issue=2;spage=197;epage=198;aulast=Singh
VL - 45
ER -