TY - JOUR
KW - Adolescent
KW - Adult
KW - Aged
KW - Biomarkers
KW - Brazil
KW - Child
KW - Female
KW - Hepatitis B
KW - Hepatitis B Antibodies
KW - Hepatitis B Antigens
KW - Humans
KW - Inpatients
KW - leprosy
KW - Leprosy, Borderline
KW - Male
KW - Middle Aged
KW - Outpatients
KW - Prevalence
KW - Seroepidemiologic Studies
AU - Rosa H
AU - Costa A P
AU - Ferraz M L
AU - Pedroza S C
AU - Andrade A L
AU - Martelli C M
AU - Zicker F
AB - <p>This investigation presents the results of hepatitis B virus screening among leprosy patients conducted in central Brazil as a preliminary information for a HBV vaccination programme. The main objectives were to assess the seroprevalence of HBV serum markers among lepromatous patients and to analyse institutionalization as risk factor for HBV infection in this population. Two groups of lepromatous patients were studied, 83 outpatients and 171 institutionalized ones. Screening for HBV serum markers included the detection of HBsAg, anti-HBc by radioimmune assay (RIA). The prevalence of carrier state (HBsAg) was 4.8% and 8.8% among outpatients and institutionalized, respectively, (p > 0.05). Seroprevalence of exposure (all markers) was statistically significant different between outpatients (16.9%) and institutionalized ones (50.3%). Institutionalized patients had an almost four fold risk of HBV infection when compared to the outpatients, and the highest risks were among patients with more than 21 years of residence in the colony, after adjusting for age and sex.</p>
BT - Revista do Instituto de Medicina Tropical de Sao Paulo
C1 - http://www.ncbi.nlm.nih.gov/pubmed/1342105?dopt=Abstract
DA - 1992 Sep-Oct
IS - 5
J2 - Rev. Inst. Med. Trop. Sao Paulo
LA - eng
N2 - <p>This investigation presents the results of hepatitis B virus screening among leprosy patients conducted in central Brazil as a preliminary information for a HBV vaccination programme. The main objectives were to assess the seroprevalence of HBV serum markers among lepromatous patients and to analyse institutionalization as risk factor for HBV infection in this population. Two groups of lepromatous patients were studied, 83 outpatients and 171 institutionalized ones. Screening for HBV serum markers included the detection of HBsAg, anti-HBc by radioimmune assay (RIA). The prevalence of carrier state (HBsAg) was 4.8% and 8.8% among outpatients and institutionalized, respectively, (p > 0.05). Seroprevalence of exposure (all markers) was statistically significant different between outpatients (16.9%) and institutionalized ones (50.3%). Institutionalized patients had an almost four fold risk of HBV infection when compared to the outpatients, and the highest risks were among patients with more than 21 years of residence in the colony, after adjusting for age and sex.</p>
PY - 1992
SP - 421
EP - 6
T2 - Revista do Instituto de Medicina Tropical de Sao Paulo
TI - Association between leprosy and hepatitis B infection. A survey in Goiânia, central Brazil.
VL - 34
SN - 0036-4665
ER -