Leprosy is an ancient disease that remains endemic and continues to be a major public health problem in some tropical countries, where it has been internationally recognized as being linked to the underdevelopment conditions. The natural course of the disease covers a wide variety of clinical conditions with systemic involvement. In this paper, we review the findings obtained in studies of the pathological mechanisms of leprosy, including a survey of the literature and of our own work. The understanding and control of the wide variety of clinical conditions should help improve patient care and thus prevent the onset of physical impairment and the stigma of the disease.
BT - Memorias do Instituto Oswaldo Cruz C1 - http://www.ncbi.nlm.nih.gov/pubmed/23283450?dopt=Abstract CN - FOSS 2012 DA - 2012 Dec DO - 10.1590/s0074-02762012000900006 J2 - Mem. Inst. Oswaldo Cruz LA - eng N2 -Leprosy is an ancient disease that remains endemic and continues to be a major public health problem in some tropical countries, where it has been internationally recognized as being linked to the underdevelopment conditions. The natural course of the disease covers a wide variety of clinical conditions with systemic involvement. In this paper, we review the findings obtained in studies of the pathological mechanisms of leprosy, including a survey of the literature and of our own work. The understanding and control of the wide variety of clinical conditions should help improve patient care and thus prevent the onset of physical impairment and the stigma of the disease.
PY - 2012 SP - 28 EP - 33 T2 - Memorias do Instituto Oswaldo Cruz TI - Leprosy, a neglected disease that causes a wide variety of clinical conditions in tropical countries. UR - http://www.scielo.br/pdf/mioc/v107s1/06.pdf VL - 107 Suppl 1 SN - 1678-8060 ER -