Despite the huge effort and massive advances toward the elimination of leprosy over the last two decades, the disease has proven stubborn; new case detection rates have stabilised over the last few years and leprosy remains endemic in a number of localised regions. The American Leprosy Missions and Infectious Disease Research Institute have undertaken a large research effort aimed at developing new tools and a vaccine to continue the push for leprosy elimination. In this paper, we outline our strategy for the integration of rapid diagnostic tests and lab-based assays to facilitate the detection of early or asymptomatic leprosy cases, as well as the efficient and focused implementation of chemoprophylaxis and immunisation to intervene in leprosy development and transmission.
BT - Memorias do Instituto Oswaldo Cruz C1 - http://www.ncbi.nlm.nih.gov/pubmed/23283471?dopt=Abstract CN - DUTHIE 2012 DA - 2012 Dec DO - 10.1590/s0074-02762012000900027 J2 - Mem. Inst. Oswaldo Cruz LA - eng N2 -Despite the huge effort and massive advances toward the elimination of leprosy over the last two decades, the disease has proven stubborn; new case detection rates have stabilised over the last few years and leprosy remains endemic in a number of localised regions. The American Leprosy Missions and Infectious Disease Research Institute have undertaken a large research effort aimed at developing new tools and a vaccine to continue the push for leprosy elimination. In this paper, we outline our strategy for the integration of rapid diagnostic tests and lab-based assays to facilitate the detection of early or asymptomatic leprosy cases, as well as the efficient and focused implementation of chemoprophylaxis and immunisation to intervene in leprosy development and transmission.
PY - 2012 SP - 190 EP - 6 T2 - Memorias do Instituto Oswaldo Cruz TI - The potential for vaccination in leprosy elimination: new tools for targeted interventions. UR - http://www.scielo.br/pdf/mioc/v107s1/27.pdf VL - 107 Suppl 1 SN - 1678-8060 ER -